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TEDTALK The agony of opioid withdrawal — and what doctors should tell patients about it

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  1. haywire
    wire for tying up bales of hay
    As the symptoms dialed up in intensity, my internal thermostat seemed to go haywire.
  2. thermostat
    a regulator for automatically regulating temperature
    As the symptoms dialed up in intensity, my internal thermostat seemed to go haywire.
  3. taper
    diminish gradually
    I was given what I now know is a much too aggressive tapering regimen, according to which I divided my medication into four doses, dropping one each week over the course of the month.
  4. withdrawal
    the termination of drug taking
    The result is that I was launched into acute opioid withdrawal.
  5. prescribe
    issue commands or orders for
    Sadiye became concerned, and she called the prescribing doctor who very helpfully advised lots of fluids for the nausea.
  6. purview
    the range of interest or activity that can be anticipated
    The pain docs saw their job as getting pain under control and when I couldn't get off the medication, they saw me as the purview of addiction medicine.
  7. orthopedic
    of or relating to the treatment of bones or joints
    So I was back in my orthopedic surgeon's office for yet another follow-up appointment.
  8. nauseated
    feeling queasy, as though one is about to vomit
    I became nauseated, lost my appetite, I ached everywhere, had increased pain in my rather mangled foot; I developed trouble sleeping due to a general feeling of restlessness.
  9. neural
    of or relating to the nervous system
    At the time they felt like a neural misfire, similar to the goosebumps.
  10. regimen
    a systematic plan for therapy
    I was given what I now know is a much too aggressive tapering regimen, according to which I divided my medication into four doses, dropping one each week over the course of the month.
  11. prescription
    the action of issuing authoritative rules or directions
    00:49 In two months of escalating prescriptions, this was the first time that anyone had expressed concern.
  12. addiction
    being dependent on something habit-forming
    The pain docs saw their job as getting pain under control and when I couldn't get off the medication, they saw me as the purview of addiction medicine.
  13. indefensible
    not capable of being justified or explained
    America's epidemic is far bigger than that, but when a medication is responsible for tens of thousands of deaths a year, reckless management of that medication is indefensible.
  14. wean
    detach the affections of
    "Look," he told us, "my initial advice to you is clearly bad, so my official recommendation is that Travis go back on the medication until he can find someone more competent to wean him off."
  15. ceramic
    an artifact made of clay baked at a high temperature
    I alternated between cooling my feverish head against the ceramic tiles and trying violently to throw up despite not having eaten anything in days.
  16. insomnia
    an inability to sleep
    06:24 The insomnia became unbearable and after two days with virtually no sleep, I spent a whole night on the floor of our basement bathroom.
  17. desperation
    a state in which all hope is lost or absent
    Several times a day I would get that welling in my chest where you know the tears are coming, but I couldn't stop them and with them came desperation and hopelessness.
  18. profusely
    in very large amounts or quantities; extremely
    I would sweat profusely almost constantly, and yet if I managed to get myself out into the hot August sun, I might look down and find myself covered in goosebumps.
  19. escalate
    increase in extent or intensity
    00:49 In two months of escalating prescriptions, this was the first time that anyone had expressed concern.
  20. nonchalant
    marked by casual unconcern or indifference
    I was nonchalant, having given this information to many doctors many times before, but this time was different.
  21. dependence
    the state of relying on someone or something else
    My dependence on opioids was entirely predictable given the amount that I was prescribed and the duration for which I was prescribed it.
  22. trauma
    an emotional wound or shock having long-lasting effects
    01:09 What happened next really came to define my entire experience of medical trauma.
  23. meaningful
    having a purpose
    The tears that had felt like a misfire before now felt meaningful.
  24. writhing
    moving in a twisting or snake-like or wormlike fashion
    I basically stopped eating, and I barely slept at all thanks to the jitters that would keep me writhing all night.
  25. unbearable
    incapable of being put up with
    06:24 The insomnia became unbearable and after two days with virtually no sleep, I spent a whole night on the floor of our basement bathroom.
  26. mangle
    destroy or injure severely
    I became nauseated, lost my appetite, I ached everywhere, had increased pain in my rather mangled foot; I developed trouble sleeping due to a general feeling of restlessness.
  27. facility
    a building or place that provides a particular service
    When my desperation was clearly coming through my voice, much as it is now, the receptionist took a deep breath and said, "Mr. Rieder, it sounds like perhaps what you need is a rehab facility or a methadone clinic."
  28. virtually
    in essence or in effect but not in fact
    06:24 The insomnia became unbearable and after two days with virtually no sleep, I spent a whole night on the floor of our basement bathroom.
  29. seemingly
    from appearances alone
    I would find myself with tears coming on for seemingly no reason and with no warning.
  30. initially
    at the beginning
    Well, after I initially published my story in an academic journal, someone from the CDC sent me their pocket guide for tapering opioids.
  31. twitch
    make an uncontrolled, short, jerky motion
    It was a deep sense of jitters that would keep me twitching.
  32. recipe
    directions for making something
    10:31 This is a recipe for disaster and any such disaster would be interesting and worth talking about -- probably worth a TED Talk -- but the failure of opioid tapering is a particular concern at this moment in America because we are in the midst of an epidemic in which 33,000 people died from overdose in 2015.
  33. core
    the choicest or most vital part of some idea or experience
    But I believed it to my core because I no longer had any hope that I would be normal again.
  34. crucial
    of extreme importance; vital to the resolution of a crisis
    But focusing only on the rate of prescribing risks overlooking two crucially important points.
  35. duration
    the period of time during which something continues
    My dependence on opioids was entirely predictable given the amount that I was prescribed and the duration for which I was prescribed it.
  36. abate
    become less in amount or intensity
    I fell asleep, I slept through the night and when I woke up, the most severe symptoms had abated dramatically.
  37. judicious
    marked by the exercise of common sense in practical matters
    And second: we can still fight the epidemic while judiciously prescribing opioids to people who really need them by requiring that doctors properly manage the pills that they do prescribe.
  38. feverish
    having or affected by an abnormally high body temperature
    I alternated between cooling my feverish head against the ceramic tiles and trying violently to throw up despite not having eaten anything in days.
  39. gear
    a toothed wheel that engages another toothed mechanism
    I hung up and I started calling those places, but it took me virtually no time at all to discover that many of these facilities are geared towards those battling long-term substance use disorder.
  40. fluid
    a substance that is liquid at room temperature and pressure
    Sadiye became concerned, and she called the prescribing doctor who very helpfully advised lots of fluids for the nausea.
  41. intensity
    high level or degree
    As the symptoms dialed up in intensity, my internal thermostat seemed to go haywire.
  42. unique
    the single one of its kind
    This story is important precisely because I'm not special; because nothing that happened to me was all that unique.
  43. acute
    extremely sharp or intense
    The result is that I was launched into acute opioid withdrawal.
  44. reckless
    marked by defiant disregard for danger or consequences
    America's epidemic is far bigger than that, but when a medication is responsible for tens of thousands of deaths a year, reckless management of that medication is indefensible.
  45. competent
    properly or sufficiently qualified, capable, or efficient
    "Look," he told us, "my initial advice to you is clearly bad, so my official recommendation is that Travis go back on the medication until he can find someone more competent to wean him off."
  46. barely
    in a sparse or scanty way
    I basically stopped eating, and I barely slept at all thanks to the jitters that would keep me writhing all night.
  47. furious
    marked by extreme anger
    Furious, we called the prescriber back and begged him for anything -- anything that could help me -- but instead he apologized, saying that he was out of his depth.
  48. agony
    intense feelings of suffering; acute mental or physical pain
    I was in agony.
  49. instance
    an item of information that is typical of a class or group
    So for instance, we're now gaining evidence that American physicians often prescribe medication even when it's not necessary in the case of opioids.
  50. launch
    propel with force
    The result is that I was launched into acute opioid withdrawal.
  51. entire
    constituting the full quantity or extent; complete
    01:09 What happened next really came to define my entire experience of medical trauma.
  52. consume
    spend extravagantly
    These sorts of considerations help to explain why America, despite accounting for only five percent of the global population, consumes nearly 70 percent of the total global opioid supply.
  53. assume
    take to be the case or to be true
    I assumed I would die --
  54. gather
    assemble or get together
    09:11 So -- I'm sorry, I have to gather myself just a little bit.
  55. assure
    inform positively and with certainty and confidence
    As somebody who has had severe, real, long-lasting pain, I can assure you these medications can make life worth living.
  56. admit
    declare to be true or accept the reality of
    08:09 After being turned away from a rehab facility, I finally admitted defeat.
Created on Fri Aug 28 06:29:57 EDT 2020 (updated Fri Aug 28 06:38:56 EDT 2020)

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