If you feel pain, you feel acute physical or emotional discomfort. A sprained ankle will pain you. So will news of a loved one's death. If you "take pain" over something, it means you're being careful.

An annoying person can be described as a pain––it's understood that they don't cause you actual physical pain, but cause you emotional discomfort and distress. You can also describe this person as a "pain in the neck," "a pain in the butt," or "a royal pain."

Definitions of pain
  1. noun
    a somatic sensation of acute discomfort
    “as the intensity increased the sensation changed from tickle to pain
    synonyms: pain sensation, painful sensation
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    pain in the area of the ovary that is felt at the time of ovulation (usually midway through the menstrual cycle)
    phantom limb pain
    pain felt by an amputee that seems to be located in the missing limb
    a sharp stab of pain
    type of:
    somaesthesia, somatesthesia, somatic sensation, somesthesia
    the perception of tactual or proprioceptive or gut sensations
  2. noun
    a symptom of some physical hurt or disorder
    “the patient developed severe pain and distension”
    synonyms: hurting
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    ache, aching
    a dull persistent (usually moderately intense) pain
    agony, excruciation, suffering
    a state of acute pain
    pain in a joint or joints
    burn, burning
    pain that feels hot as if it were on fire
    a burning pain in a limb along the course of a peripheral nerve; usually associated with skin changes
    colic, gripes, griping, intestinal colic
    acute abdominal pain (especially in infants)
    chest pain
    pain in the chest
    a pain in the hand that is not traumatic
    extreme physical pain
    painful menstruation
    glossalgia, glossodynia
    pain in the tongue
    growing pains
    pain in muscles or joints sometimes experienced by children and often attributed to rapid growth
    haemorrhoid, hemorrhoid, piles
    pain caused by venous swelling at or inside the anal sphincter
    pain in the cornea
    labor pain
    pain and discomfort associated with contractions of the uterus during labor
    pain in the breast
    rheumatic or myalgic pains in the arms or legs
    pain in the thigh
    pain in the uterus
    myalgia, myodynia
    pain in a muscle or group of muscles
    pain in the kidney (usually felt in the loins)
    neuralgia, neuralgy
    acute spasmodic pain along the course of one or more nerves
    severe pain on swallowing due to a disorder of the esophagus
    pain in the testes
    a sharp spasm of pain
    pang, sting
    a mental pain or distress
    photalgia, photophobia
    pain in the eye resulting from exposure to bright light (often associated with albinism)
    costalgia, pleuralgia, pleurodynia
    pain in the chest caused by inflammation of the muscles between the ribs
    foot pain
    pain in the rectum
    referred pain
    pain that is felt at a place in the body different from the injured or diseased part where the pain would be expected
    renal colic
    sharp pain in the lower back that radiates into the groin; associated with the passage of a renal calculus through the ureter
    smart, smarting, smartness
    a kind of pain such as that caused by a wound or a burn or a sore
    sting, stinging
    a kind of pain; something as sudden and painful as being stung
    a sharp spasm of pain in the side resulting from running
    rawness, soreness, tenderness
    a pain that is felt (as when the area is touched)
    pain caused by heat
    a deep pulsating type of pain
    torment, torture
    unbearable physical pain
    pain in the gums
    pain during urination
    soreness or irritation of the skin caused by friction
    lead colic, painter's colic
    symptom of chronic lead poisoning and associated with obstinate constipation
    odontalgia, toothache
    an ache localized in or around a tooth
    severe spasm of pain
    Passion, Passion of Christ
    the suffering of Jesus at the Crucifixion
    an ache localized in the back
    primary dysmenorrhea
    painful menstruation that is intrinsic to menstruation and not the result of a disease
    secondary dysmenorrhea
    painful menstruation that is caused by some specific disorder (as endometriosis)
    cephalalgia, head ache, headache
    pain in the head caused by dilation of cerebral arteries or muscle contractions or a reaction to drugs
    bellyache, gastralgia, stomach ache, stomachache
    an ache localized in the stomach or abdominal region
    earache, otalgia
    an ache localized in the middle or inner ear
    tic douloureux, trigeminal neuralgia
    intense paroxysmal neuralgia along the trigeminal nerve
    neuralgia along the sciatic nerve
    birth pangs, labor pains, labour pains
    a regularly recurrent spasm of pain that is characteristic of childbirth
    pains felt by a woman after her baby is born; associated with contractions of the uterus
    rebound tenderness
    pain felt when a hand pressing on the abdomen is suddenly released; a symptom of peritoneal inflammation
    soreness and warmth caused by friction
    type of:
    (medicine) any sensation or change in bodily function that is experienced by a patient and is associated with a particular disease
  3. noun
    emotional distress; a fundamental feeling that people try to avoid
    “the pain of loneliness”
    synonyms: painfulness
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    pleasance, pleasure
    a fundamental feeling that is hard to define but that people desire to experience
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    growing pains
    emotional distress arising during adolescence
    the feeling caused by disagreeable stimuli; one pole of a continuum of states of feeling
    mental anguish
    sustained dull painful emotion
    hurt, suffering
    feelings of mental or physical pain
    distress, hurt, suffering
    psychological suffering
    agony, torment, torture
    intense feelings of suffering; acute mental or physical pain
    violent pangs of suffering
    discomfort, irritation, soreness
    an uncomfortable feeling of mental painfulness or distress
    anguish, torment, torture
    extreme mental distress
    self-torment, self-torture
    self-imposed distress
    (Yiddish) trouble and suffering
    a figurative injury (to your feelings or pride)
    type of:
    the experiencing of affective and emotional states
  4. noun
    something or someone that causes trouble; a source of unhappiness
    synonyms: annoyance, bother, botheration, infliction, pain in the ass, pain in the neck
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    (law) a broad legal concept including anything that disturbs the reasonable use of your property or endangers life and health or is offensive
    irritant, thorn
    something that causes irritation and annoyance
    an annoyance
    abatable nuisance
    a nuisance that can remedied (suppressed or extinguished or rendered harmless)
    attractive nuisance
    anything on your premises that might attract children into danger or harm
    mixed nuisance
    a nuisance that is both a public nuisance and a private nuisance at the same time
    private nuisance
    a nuisance that interferes with your interest in and private use and enjoyment of your land
    common nuisance, public nuisance
    a nuisance that unreasonably interferes with a right that is common to the general public
    type of:
    negative stimulus
    a stimulus with undesirable consequences
  5. noun
    a bothersome annoying person
    “that kid is a terrible pain
    synonyms: nuisance, pain in the neck
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    type of:
    disagreeable person, unpleasant person
    a person who is not pleasant or agreeable
  6. verb
    cause bodily suffering to and make sick or indisposed
    synonyms: ail, trouble
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    break out, erupt, recrudesce
    become raw or open
    type of:
    give trouble or pain to
  7. verb
    cause emotional anguish or make miserable
    “It pains me to see my children not being taught well in school”
    synonyms: anguish, hurt
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    break someone's heart
    cause deep emotional pain and grief to somebody
    agonise, agonize
    cause to agonize
    give pain or trouble to
    excruciate, rack, torment, torture
    torment emotionally or mentally
    type of:
    discomfit, discompose, disconcert, rattle, untune, upset
    cause to lose one's composure
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