Unless you can find someone to pay you to sip fancy tropical drinks on the beach, your vocation is not likely to be a vacation. Rather, the word means something you know how to do––or what you do for a living.
The word vocation derives from the Latin vocare "to call." To become a priest, you need to feel that you have been "called" to the ministry directly by God. Their job is their calling, or vocation. An avocation is something you do because you love it. Everyone should make it their goal to have their avocation become their vocation.