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Taking Ketamine and Looking at Smiling Faces is a Therapy That Could Help End Depression, Shows Clinical Trial

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  1. plasticity
    the property of being physically malleable
    The scientists behind the plan have found depression can be kept at bay for at least a month if the digital techniques are used when ketamine has prepared the brain’s plasticity.
  2. intravenous
    within or by means of a vein
    As a result, Dr Price and her team are reorienting their goals to improve access to intravenous ketamine treatment and boost its effect by pairing the drug with digital therapies.
  3. randomize
    arrange or organize by chance, without any order or plan
    The results of the double-blind, randomized clinical trial conducted locally in Pennsylvania were published last month in the American Journal of Psychiatry.
  4. reorient
    determine one's position once again
    As a result, Dr Price and her team are reorienting their goals to improve access to intravenous ketamine treatment and boost its effect by pairing the drug with digital therapies.
  5. infusion
    the act of introducing a modifying element or quality
    Though symptom relief can be felt just two hours after a ketamine infusion, the drug’s effects often wear off after a couple of weeks meaning patients go back for more.
  6. psychedelic
    producing distorted sensory perceptions and feelings
    MORE: Another Study Shows Psychedelic Psilocybin Mushrooms Offering Long-Term Relief From Depressive Symptoms
  7. repurpose
    adapt for a new use or format
    “This automated intervention is so simple that it could be repurposed to address a variety of mental health conditions and easily tweaked to match the needs of an individual patient,” said Price, who was among the first to show that intravenous ketamine can reduce suicidal thoughts
  8. illicit
    contrary to accepted morality or convention
    Being given an illicit drug called ketamine and then looking at smiling faces could help end depression, according to a new study.
  9. tweak
    adjust finely
    “This automated intervention is so simple that it could be repurposed to address a variety of mental health conditions and easily tweaked to match the needs of an individual patient,” said Price, who was among the first to show that intravenous ketamine can reduce suicidal thoughts
  10. saline
    containing salt
    A third group received a saline infusion followed by the active training.
  11. intervention
    the act of putting something between two things
    “Training the brain to link perceptions of yourself with positive ideas during this ketamine-primed plasticity window exceeded my expectations. “I was surprised and amazed to get such clear findings from an intervention that was so minimal.”
  12. remission
    an abatement in intensity or degree
    For people with such treatment-resistant depression, psychoactive drugs, such as ketamine, offer an alternative chance at long-term remission.
  13. leverage
    the mechanical advantage gained by a machine on a fulcrum
    “We are interested in creating an automated intervention that any computer or device can run, making it as accessible as possible. CHECK OUT: Phase 3 Trial of MDMA Therapy for Severe PTSD is So Successful That 67% Don’t Qualify For Diagnosis Now “Our goal is to leverage digital technologies and develop a strategy that will efficiently extend time between appointments, save patients money and get more patients effective depression care.”
  14. provisional
    under terms not final or fully worked out or agreed upon
    Based on the findings, Pittsburgh’s Innovation Institute filed a provisional patent for the treatment method, to benefit those who have exhausted all other options.
  15. bay
    an indentation of a shoreline smaller than a gulf
    The scientists behind the plan have found depression can be kept at bay for at least a month if the digital techniques are used when ketamine has prepared the brain’s plasticity.
Created on Sat Oct 08 09:36:36 EDT 2022

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