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  1. misstate
    state something incorrectly
    This article has been revised to reflect the following correction: Correction: April 10, 2013 An earlier version of this article misstated Dr. Clay Reid’s work with Dr. Jeff Lichtman of Harvard.
  2. slice up
    cut into slices
    Read All Comments (86) » Scientists at Stanford University reported on Wednesday that they have made a whole mouse brain, and part of a human brain, transparent so that networks of neurons that receive and send information can be highlighted in stunning color and viewed in all their three-dimensional complexity without slicing up the organ.
  3. Jell-O
    fruit-flavored dessert (trade mark Jell-O) made from a commercially prepared gelatin powder
    The visible brain has arrived — the consistency of Jell-O, as transparent and colorful as a child’s model, but vastly more useful.
  4. permeate
    spread or diffuse through
    Dr. Chung said the hydrogel forms a kind of mesh that permeates the brain and connects to most of the molecules, but not to the lipids, which include fats and some other substances.
  5. schizophrenia
    a psychotic disorder characterized by distortions of reality
    The researchers say this process may help uncover the physical underpinnings of devastating mental disorders like schizophrenia, autism, post-traumatic stress disorder and others.
  6. traumatic
    psychologically painful
    The researchers say this process may help uncover the physical underpinnings of devastating mental disorders like schizophrenia, autism, post-traumatic stress disorder and others.
  7. bipolar
    pertaining to or occurring in northern and southern extremes
    Techniques like this, said Dr. Insel, “should give us a much more precise picture of what is happening in the brains of people who have schizophrenia, autism, post-traumatic stress disorder, bipolar disorder and depression.”
  8. Reid
    Scottish philosopher of common sense who opposed the ideas of David Hume (1710-1796)
    “I think it’s great,” said Dr. Clay Reid, a senior investigator at the Allen Institute for Brain Science in Seattle, who was not involved in the work.
  9. infuse
    fill, as with a certain quality
    Once they are out, the brain is transparent, and its biochemistry is intact, so it may be infused with chemicals, like antibody molecules that also have a dye attached, that show fine details of its structure and previous activity.
  10. mesh
    an open fabric woven together at regular intervals
    Dr. Chung said the hydrogel forms a kind of mesh that permeates the brain and connects to most of the molecules, but not to the lipids, which include fats and some other substances.
  11. anatomical
    of or relating to the branch of morphology that studies the structure of organisms
    Dr. Thomas Insel, director of the National Institute of Mental Health, which provided some of the financing for the research, described the new work as helping to build an anatomical “foundation” for the Obama initiative, which is meant to look at activity in the brain.
  12. solidity
    the consistency of a solid
    The key to the new technique is a substance called a hydrogel, a material that is mostly water held together by larger molecules to give it some solidity.
  13. stunning
    causing bewilderment, shock, or insensibility
    Read All Comments (86) » Scientists at Stanford University reported on Wednesday that they have made a whole mouse brain, and part of a human brain, transparent so that networks of neurons that receive and send information can be highlighted in stunning color and viewed in all their three-dimensional complexity without slicing up the organ.
  14. probe
    an exploratory action or expedition
    The work, reported on Wednesday in the journal Nature, is not part of the Obama administration’s recently announced initiative to probe the secrets of the brain, although the senior author on the paper, Dr. Karl Deisseroth at Stanford, was one of those involved in creating the initiative and is involved in planning its future.
  15. recipe
    directions for making something
    But with the paper’s publication, the recipe is now available to anyone who wants to use it, and, he said, “I think it will be relatively easy.”
  16. consistency
    uniformity or stability in arrangement, behavior, or quality
    The visible brain has arrived — the consistency of Jell-O, as transparent and colorful as a child’s model, but vastly more useful.
  17. spectacular
    sensational in appearance or thrilling in effect
    “Frankly,” he said, “that is spectacular.”
  18. logo
    a company emblem or device
    Science Twitter Logo.
  19. bench
    a long seat for more than one person
    On his laboratory bench, he said, “I have a transparent liver, lungs and heart.”
  20. Allen
    a soldier of the American Revolution whose troops helped capture Fort Ticonderoga from the British (1738-1789)
    “I think it’s great,” said Dr. Clay Reid, a senior investigator at the Allen Institute for Brain Science in Seattle, who was not involved in the work.
  21. Seattle
    a major port of entry and the largest city in Washington
    “I think it’s great,” said Dr. Clay Reid, a senior investigator at the Allen Institute for Brain Science in Seattle, who was not involved in the work.
Created on Fri Apr 12 22:01:27 EDT 2013

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