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  1. meiosis
    cell division that produces reproductive cells
    Meiosis is the mode of cell replication for the formation of sperm and egg cells in plants, animals, and many other multicellular life forms.
  2. mutation
    a change or alteration in form or qualities
    There are many diseases caused by mutations in mitochondrial DNA (mtDNA).
  3. recessive
    of or pertaining to a recession
    These factors each exhibit a characteristic dominant, co-dominant, or recessive expression, and those that are dominant will mask the expression of those that are recessive.
  4. splice
    join the ends of
    Ribonucleic Acids
    In addition to mRNA, DNA codes for other forms of RNA, including ribosomal RNAs (rRNAs), transfer RNAs (tRNAs), and small nuclear RNAs (snRNAs). rRNAs and tRNAs participate in protein assembly whereas snRNAs aid in a process called splicing -the process of editing of mRNA before it can be used as a template for protein synthesis.
  5. annotate
    add explanatory notes to or supply with critical comments
    However, we still have to make guesses at the actual number of genes, because not all of the human genome sequence is annotated and not all of the known sequence has been assigned a particular position in the genome.
  6. replicate
    reproduce or make an exact copy of
    This redundancy is key to accommodating mutations that occur naturally as DNA is replicated and new cells are produced.
  7. synthesis
    the combination of ideas into a complex whole
    This complementary base pairing is what makes DNA a suitable molecule for carrying our genetic information-one strand of DNA can act as a template to direct the synthesis of a complementary strand.
  8. helix
    a curve that lies on the surface of a cylinder or cone
    The chemical nature of the bases in double-stranded DNA creates a slight twisting force that gives DNA its characteristic gently coiled structure, known as the double helix.
  9. morph
    cause to change shape in a computer animation
    This means that the gene's sequence is slightly different in the two individuals, and the gene is said to be polymorphic, "poly" meaning many and "morph" meaning shape or form.
  10. pigment
    dry coloring material
    When you look at the human species, you see evidence of a process called genetic variation, that is, there are immediately recognizable differences in human traits, such as hair and eye color, skin pigment, and height.
  11. transcribe
    write out, as from speech or notes
    Both exons and introns are "transcribed" into mRNA, but before it is transported to the ribosome, the primary mRNA transcript is edited.
  12. connective
    connecting or tending to connect
    An example is Marfan's syndrome, where there is a defect in the gene coding for a connective tissue protein.
  13. translation
    rendering in another language with the same meaning
    This must be done both during the transcription and the translation process.
  14. synonymous
    meaning the same or nearly the same
    Mutations can either be synonymous, in which the variation still results in a codon for the same amino acid or non-synonymous, in which the variation results in a codon for a different amino acid.
  15. blueprint
    something intended as a guide for making something else
    Molecular Genetics: The Study of Heredity, Genes, and DNA

    As we have just learned, DNA provides a blueprint that directs all cellular activities and specifies the developmental plan of multicellular organisms.
  16. complement
    something added to embellish or make perfect
    This process creates a stretch of hybrid DNA (bottom panel) in which the single strand of one duplex is paired with its complement from the other duplex.
  17. mask
    a covering to disguise or conceal the face
    These factors each exhibit a characteristic dominant, co-dominant, or recessive expression, and those that are dominant will mask the expression of those that are recessive.
  18. ready-made
    made for purchase and immediate use
    In the adult, red blood cells do not contain DNA for making new globin; they are ready-made with all of the hemoglobin they will need.
  19. minimal
    the least possible
    Genetic mutations occur randomly, and the effect of a small number of mutations on a single gene may be minimal.
  20. progression
    the act of moving forward, as toward a goal
    However, evidence suggests that the mutations contribute to the progression of both diseases.
  21. scenario
    a postulated sequence of possible events
    Because mitochondria have their own DNA, RNA, and ribosomes, this scenario is quite possible.
  22. gender
    properties that distinguish organisms on the basis of sex
    Subsequently, genes on that chromosome that do not code for gender are expressed in the male phenotype, even if they are recessive.
  23. hybrid
    the offspring of genetically dissimilar parents or stock
    This process creates a stretch of hybrid DNA (bottom panel) in which the single strand of one duplex is paired with its complement from the other duplex.
  24. production
    the act or process of making something
    The location and base sequence of each promoter site vary for prokaryotes (bacteria) and eukaryotes (higher organisms), but they are both recognized by RNA polymerase, which can then grab hold of the sequence and drive the production of an mRNA.
  25. analysis
    abstract separation of something into its various parts
    For example, mtDNA analysis has been used to trace the migration of people from Asia across the Bering Strait to North and South America.
  26. perform
    get done
    They perform such functions as transporting nutrients into the cell; synthesizing new DNA, RNA, and protein molecules; and transmitting chemical signals from outside to inside the cell, as well as throughout the cell-both critical to the process of making proteins.
  27. novel
    an extended fictional work in prose
    It is still unclear what all the functions of introns are, but scientists believe that some serve as the site for recombination, the process by which progeny derive a combination of genes different from that of either parent, resulting in novel genes with new combinations of exons, the key to evolution.
Created on Fri Oct 21 10:54:37 EDT 2011

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