If something has a negative association attached to it, call this a stigma. Bed-wetting can lead to a social stigma for a six-year-old, while chewing tobacco might have the same effect for a sixty-year-old.
Stigma, from the Greek word of the same spelling meaning "mark, puncture," came into English through Latin to mean a mark burned into the skin to signify disgrace. It did not take long for stigma to be used figuratively, as it is commonly used today, for the negative stereotype or reputation attached to something. If a politician is caught taking bribes, she might resign because of the stigma.