To derange someone is to make her go crazy or completely confuse her. Going without sleep for an entire week can derange a person.

It's more common to see the adjective deranged — or insane — than the verb derange, but you can use it to describe what happens when someone or something drives a person batty. Too many head injuries can derange a football player's short term memory, and a teasing cat just out of reach might derange a tied-up dog in a yard. The Old French root of derange is desrengier, "throw into disorder," which combines des, "do the opposite of" and rengier, "put into line."

Definitions of derange

v derange mentally, throw out of mental balance; make insane

Type of:
craze, madden
cause to go crazy; cause to lose one's mind

v throw into great confusion or disorder

perturb, throw out of kilter
Type of:
disarray, disorder
bring disorder to

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