When you administer something, you give it to others. This can apply to a dose of medicine, an order, a survey, or a punishment. Administer can also mean to run something — such as a school or an office.
The word administer belongs to a family of words, all having to do with being in charge: administration, administrator, and administrative. Strangely, administer comes from the Latin word minister meaning "servant." So, if your boss or principal administers an instruction that you disagree with, just think of that person as your servant. Doing so will help you carry out your duties with a smile.