the process in reproduction and growth by which a cell divides to form daughter cells
The findings pertain to mRNAs that help regulate cell division and could therefore have implications for reversing cancer's out-of-control cell division.
the substance inside a cell, not including the nucleus
But for proteins to be made, a gene's DNA code must be copied, or transcribed, onto mRNA molecules, which migrate from the nucleus and into the cytoplasm where the cell's protein-making machinery is located.
a nucleic acid that helps synthesize proteins and transmit genetic data
Built-In "Self-Destruct Timer" Causes Ultimate Death Of Messenger RNA In Cells
Main Category: Biology / Biochemistry
Also Included In: Genetics
Article Date: 24 Dec 2011 - 0:00 PST
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The Einstein scientists found that the promoter regions of the SWI5 and CLB2 genes do something else as well: they recruit a protein called Dbf2p, which jumps onto mRNA molecules as they're being synthesized.
the study of substances and processes inside living things
Built-In "Self-Destruct Timer" Causes Ultimate Death Of Messenger RNA In Cells
Main Category: Biology / Biochemistry
Also Included In: Genetics
Article Date: 24 Dec 2011 - 0:00 PST
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the basic structural and functional unit of all organisms
Built-In "Self-Destruct Timer" Causes Ultimate Death Of Messenger RNA In Cells
Main Category: Biology / Biochemistry
Also Included In: Genetics
Article Date: 24 Dec 2011 - 0:00 PST
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Built-In "Self-Destruct Timer" Causes Ultimate Death Of Messenger RNA In Cells
Main Category: Biology / Biochemistry
Also Included In: Genetics
Article Date: 24 Dec 2011 - 0:00 PST
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Built-In "Self-Destruct Timer" Causes Ultimate Death Of Messenger RNA In Cells
Main Category: Biology / Biochemistry
Also Included In: Genetics
Article Date: 24 Dec 2011 - 0:00 PST
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relating to the study of heredity and variation in organisms
Built-In "Self-Destruct Timer" Causes Ultimate Death Of Messenger RNA In Cells
Main Category: Biology / Biochemistry
Also Included In: Genetics
Article Date: 24 Dec 2011 - 0:00 PST
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In their search for such a mechanism, Dr. Singer and his colleagues focused on two genes, SWI5 and CLB2, which code for proteins that regulate the cell cycle, the complex series of steps during which a cell divides, first duplicating its genetic material and then distributing it evenly to two daughter cells.
The study was carried out in yeast cells using advanced microscope technology developed previously by Dr. Singer that has allowed scientists, for the first time, to observe single molecules in single cells in real time.
the act of providing treatment for an illness or disorder
"Once you gain insight into the mechanisms controlling the cell cycle and cell division," he noted, "you can propose targeted therapies for regulating the uncontrolled cell division that characterizes cancer."