Something skewed is slanted or off-center in some way. A picture frame or viewpoint can be skewed.
This is a word, like so many, that can apply to physical things or ideas. A painting on the wall is skewed if it's leaning to one side. Also, opinions are often skewed: this is another way of saying someone is biased. People often accuse news reports of being skewed toward one political viewpoint. A movie could be skewed toward one character more than the other. When you think of skewed, think of leaning and slanting of all sorts.