exacerbation

Definitions of exacerbation
1

n action that makes a problem or a disease (or its symptoms) worse

Synonyms:
aggravation
Type of:
intensification
action that makes something stronger or more extreme

n violent and bitter exasperation

“his foolishness was followed by an exacerbation of their quarrel”
Type of:
exasperation
actions that cause great irritation (or even anger)

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