Other forms: disaffiliated; disaffiliating; disaffiliates
To disaffiliate is to break off a connection with a person, group, or organization. If your book club has become nothing but a monthly gossip session, with no discussion of books at all, you might decide to disaffiliate from it.
Disaffiliate combines dis-, "the opposite of," with affiliate, "bring into close association," from the Latin affiliare, "to adopt a son." When someone separates themselves from some close association, they disaffiliate from it. If you no longer want to be affiliated with a group of friends, you can decide to disaffiliate. And when a church has a disagreement with its denomination, it can also disaffiliate, becoming an independent, separate.