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antagonistic

If you're antagonistic, you're hard to get along with. Harmony is not your friend — you prefer hostility and struggle.

If you're antagonistic to your little brother, you're always picking on him and giving him a hard time — causing him agony — a word that's buried in antagonistic. Even drugs or chemicals can be antagonistic: if you take a sleeping pill and then follow it with a few cups of espresso, the interaction is likely to be antagonistic. The sleeping pill and the caffeine struggle against each other and you're not likely to get much sleep.

Definitions of antagonistic
  1. adjective
    characterized by antagonism or antipathy
    “slaves antagonistic to their masters”
    synonyms: adversarial, antipathetic, antipathetical
    hostile
    characterized by enmity or ill will
  2. adjective
    incapable of harmonious association
    Synonyms:
    incompatible
    not compatible
  3. adjective
    arousing animosity or hostility
    “his antagonistic brusqueness”
    “Europe was antagonistic to the Unites States”
    Synonyms:
    alienating
    causing hostility or loss of friendliness
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    Antonyms:
    conciliative, conciliatory
    intended to placate
    appeasing, placating, placative, placatory
    intended to pacify by acceding to demands or granting concessions
    pacific
    promoting peace
    propitiative, propitiatory
    intended to reconcile or appease
    soft
    willing to negotiate and compromise
    show more antonyms...
  4. adjective
    indicating opposition or resistance
    synonyms: counter
    negative
    characterized by or displaying negation or denial or opposition or resistance; having no positive features
  5. adjective
    used especially of drugs or muscles that counteract or neutralize each other's effect
    synonyms: incompatible
    antacid
    acting to neutralize acid (especially in the stomach)
    antiphlogistic
    counteracting inflammation
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    Antonyms:
    interactive, synergistic
    used especially of drugs or muscles that work together so the total effect is greater than the sum of the two (or more)
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