antagonistic

If you're antagonistic, you're hard to get along with. Harmony is not your friend — you prefer hostility and struggle.

If you're antagonistic to your little brother, you're always picking on him and giving him a hard time — causing him agony — a word that's buried in antagonistic. Even drugs or chemicals can be antagonistic: if you take a sleeping pill and then follow it with a few cups of espresso, the interaction is likely to be antagonistic. The sleeping pill and the caffeine struggle against each other and you're not likely to get much sleep.

Definitions of antagonistic
1

adj characterized by antagonism or antipathy

“slaves antagonistic to their masters”
Synonyms:
antipathetic, antipathetical
hostile
characterized by enmity or ill will

adj incapable of harmonious association

Synonyms:
incompatible
not compatible

adj arousing animosity or hostility

“his antagonistic brusqueness”
“Europe was antagonistic to the Unites States”
Synonyms:
alienating
causing hostility or loss of friendliness
Antonyms:
conciliative, conciliatory
intended to placate
appeasing, placating, placative, placatory
intended to pacify by acceding to demands or granting concessions
pacific
promoting peace
propitiative, propitiatory
intended to reconcile or appease
soft
willing to negotiate and compromise
show more antonyms...

adj indicating opposition or resistance

Synonyms:
counter
negative
characterized by or displaying negation or denial or opposition or resistance; having no positive features

adj used especially of drugs or muscles that counteract or neutralize each other's effect

Synonyms:
incompatible
antacid
acting to neutralize acid (especially in the stomach)
antiphlogistic
counteracting inflammation
Antonyms:
interactive, synergistic
used especially of drugs or muscles that work together so the total effect is greater than the sum of the two (or more)

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