Other forms: stir-crazier; stir-craziest
If you're living in a small cabin in the woods, and it pours rain for three days straight, you're likely to get a bit stir-crazy from being cooped up inside. You'll likely be even stir-crazier if there are five of you in there, including one crying baby!
Stir-crazy is from the late 1930s. It began as prison slang, used to describe inmates who suffer genuine mental illness as a result of being confined in a cell for a long period. However, its use was quickly extended to describe the restless, anxious, or uneasy feeling that anybody who is shut up indoors, or isolated from other people, might get. A stay-at-home parent with small children might feel a little stir-crazy from time to time, especially if they can't get out and interact with other adults.