severe combined immunodeficiency

Definitions of severe combined immunodeficiency
  1. noun
    a congenital disease affecting T cells that can result from a mutation in any one of several different genes; children with it are susceptible to infectious disease; if untreated it is lethal within the first year or two of life
    synonyms: SCID, severe combined immunodeficiency disease
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    SCID resulting from mutation of a gene that codes for adenosine deaminase
    X-SCID, X-linked SCID
    SCID in male children resulting from mutation of a gene that codes for a protein on the surface of T cells that allows them to develop a growth factor receptor
    type of:
    immunological disorder in which some part of the body's immune system is inadequate and resistance to infectious diseases is reduced
    monogenic disease, monogenic disorder
    an inherited disease controlled by a single pair of genes
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