Definitions of severe combined immunodeficiency
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a congenital disease affecting T cells that can result from a mutation in any one of several different genes; children with it are susceptible to infectious disease; if untreated it is lethal within the first year or two of life
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synonyms:
SCID, severe combined immunodeficiency disease
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types:
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ADA-SCID
SCID resulting from mutation of a gene that codes for adenosine deaminase
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X-SCID, X-linked SCID
SCID in male children resulting from mutation of a gene that codes for a protein on the surface of T cells that allows them to develop a growth factor receptor
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type of:
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immunodeficiency
immunological disorder in which some part of the body's immune system is inadequate and resistance to infectious diseases is reduced
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monogenic disease, monogenic disorder
an inherited disease controlled by a single pair of genes
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ADA-SCID
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