If you've got a knack for coming up with smart comments on the fly, you're quick-witted. The most quick-witted students in a class are often the first to raise their hands to answer the teacher's question (or to supply a sarcastic remark).

Anyone whose mind is sharp can be called quick-witted, especially if they've got a great sense of humor and are speedy with a comeback. Being quick-witted is helpful during a debate or when you're playing a game with a time limit. Quick-witted comes from wit, which doesn't just mean "sense of humor," but also "intelligence."

Definitions of quick-witted

adj mentally nimble and resourceful

quick-witted debater”
“saved an embarrassing situation with quick-witted tact”
quick or skillful or adept in action or thought

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