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pleiotropy

/plaɪˈɑtrəpi/
IPA guide

Other forms: pleiotropies

When a single gene affects more than one trait in an organism, that's known as pleiotropy. It's genetic pleiotropy that makes dogs with mottled, bluish-gray coats more likely to also be deaf and blind.

Pleiotropy is most obvious when something goes wrong in an organism, causing a mutation in a gene that affects multiple characteristics. In the human disorder known as PKU, a defect in one gene causes cognitive disability, eczema, and pale skin. Some chickens have a gene that causes them to lay fewer eggs, but also gives them frizzled feathers and a high metabolism. The Greek root of pleiotropy is pleiōn, "greater in quantity."

Definitions of pleiotropy
  1. noun
    (genetics) phenomenon in which one gene influences multiple, apparently unrelated traits
    synonyms: pleiotropism
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