“Darn you!” “Go bury your head in the sand.” “You ugly nincompoop!” Each of those nasty curses is a malediction (and, I’m sure, nothing you would ever say to another human being).
A malediction is a curse. Not like the kind a witch puts on someone, but close. More like what the schoolyard bully says to hurt someone’s feelings. On purpose. Malediction has male in it, but it’s not a slur against men or boys. Mal comes from the Latin for "evil" and "diction," and as you may remember, has to do with what we say. So a malediction is an evil statement directed at someone else. Pretty nasty, if you ask me.