A locale is the specific place where something happens. If you dream of a trip to some tropical locale, Hawaii, Belize, and Costa Rica might all be on your wish list.
When you choose a locale for a big sci-fi convention, you need to make sure there's enough room for all the participants. And when you decide on a locale for an intimate party, you might stick to a cozy spot like your own living room. Locale comes from the French local, and it was originally spelled the same way. The e was eventually added to encourage correct pronunciation, with the emphasis on the last syllable.