Discombobulate is a fun, fancy word for “confuse.” If something has put you in a state where you don't know up from down and you can't spell your own name, you may be discombobulated.
Discombobulate kind of sounds like you feel when you're disoriented: bouncing around in several directions at once. Trying to say discombobulate for the first time might discombobulate you! Because of its funny sound, discombobulate is often used in a humorous way. Are you ready to assemble some furniture, or are you too discombobulated after reading the instructions?