If you're dexterous, you're good with your hands. To be dexterous is an essential trait for knitters and sleight-of-hand magicians.
The adjective dexterous often refers to skill and agility with the hands, but it can mean any skillful or clever physical movement. A kid's dexterous ball handling and footwork can aid him on the soccer field. Dexterous can also be used to describe mental skill and agility — like the dexterous handling of an uncomfortable situation at work.