Tay-Sachs disease

Definitions of Tay-Sachs disease
  1. noun
    a hereditary disorder of lipid metabolism occurring most frequently in individuals of Jewish descent in eastern Europe; accumulation of lipids in nervous tissue results in death in early childhood
    synonyms: Sachs disease, Tay-Sachs, infantile amaurotic idiocy
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    type of:
    monogenic disease, monogenic disorder
    an inherited disease controlled by a single pair of genes
    autosomal recessive defect, autosomal recessive disease
    a disease caused by the presence of two recessive mutant genes on an autosome
    a disorder of lipid metabolism; abnormal levels of certain fats accumulate in the body
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