Tragedy is a noun that indicates disaster or bad fortune. It would be a tragedy to lose your job, but an even greater tragedy to fall ill while unemployed and without health care.
First recorded in the late 14th century, the noun tragedy originally referred to a play with an unhappy ending. About a century later it also came to mean an unhappy event or a disaster. The playwright George Bernard Shaw wittily observed, "“There are two tragedies in life. One is to lose your heart's desire. The other is to gain it.” The comedian Mel Brooks defined tragedy as follows: "Tragedy is when I cut my finger. Comedy is when you walk into an open sewer and die."