SIDS

Miroslav D. (United States of America)
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  1. tachycardia
    abnormally rapid heartbeat (over 100 beats per minute)
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  2. arrhythmia
    an abnormal rate of muscle contractions in the heart
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  3. phenotype
    observable characteristics produced by genes and environment
    Spontaneous germ line mutations (sporadic de novo)nnFamilial mutationsnConfer – udelit…these mutations confer a leaky phenotype on the channelnAberrantnnVELMI DOLEZITE – relationship between leak and arrhythmia – how?
  4. cardiac arrhythmia
    an abnormal rate of muscle contractions in the heart
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  5. mutagenesis
    an event capable of causing a mutation
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezacgytitel...
  6. heterozygous
    having dissimilar alleles at corresponding chromosomal loci
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  7. hypoxia
    oxygen deficiency
    Exportnut zotero databazu na Amitov notebook!nnhypoxiannparasympathetic versus sympathetic tone?
  8. ectopic
    exhibiting ectopia
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  9. parasympathetic
    of or relating to the parasympathetic nervous system
    Exportnut zotero databazu na Amitov notebook!nnhypoxiannparasympathetic versus sympathetic tone?
  10. SIDS
    sudden and unexpected death of an apparently healthy infant during sleep
    Increased incidence of SIDS in mutant mice might be caused by cardiac arrhythmias that are induced under conditions of catecholaminergic stress.
  11. catecholamine
    any of a group of chemicals including epinephrine and norepinephrine that are produced in the medulla of the adrenal gland
    Confounding effectsnSusceptibilitynnArrhythmias in mice and patience with genetic mutations in RyR2 are almost always triggered by stress or catecholamines.
  12. medicolegal
    pertaining to legal aspects of the practice of medicine
    Ak ostane cas – co presne je PCR?, denaturing high performance liquid chromatographynnPreco 2. mutacia ma take iste mnozstvo cal2? (aktivita je vyssia aj bez PKA)nMissense mutationnMedicolegalnZistit ake su statistiky teraz (SIDS – 1/1000?)
  13. chromatography
    a process used for separating mixtures by virtue of differences in absorbency
    Ak ostane cas – co presne je PCR?, denaturing high performance liquid chromatographynnPreco 2. mutacia ma take iste mnozstvo cal2? (aktivita je vyssia aj bez PKA)nMissense mutationnMedicolegalnZistit ake su statistiky teraz (SIDS – 1/1000?)
  14. denature
    modify (as a native protein) especially by heat, acid, alkali, or ultraviolet radiation so that all of the original properties are removed or diminished
    Ak ostane cas – co presne je PCR?, denaturing high performance liquid chromatographynnPreco 2. mutacia ma take iste mnozstvo cal2? (aktivita je vyssia aj bez PKA)nMissense mutationnMedicolegalnZistit ake su statistiky teraz (SIDS – 1/1000?)
  15. polymerase
    an enzyme that catalyzes the formation of new DNA and RNA from an existing strand of DNA or RNA
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  16. postnatal
    relating to or happening in the time after giving birth
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  17. substrate
    the material that is acted upon by an enzyme
    To elicit..e.g iso elicited equal effects on heart ratesnTachycardia was induciblennThese findings siggest that this mutation in RyR2 enhances the susceptibility to arrhythmias in young mice and that the increased arrhythmogenic substrate in these mice might lead to the enhanced incidence of SIDS.
  18. neonatal
    relating to the infant during the first month after birth
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  19. preponderantly
    much greater in number or influence
    PrecedednPreponderantlynProspectivelynElectivelynProarrhythmogenicnSubsequentlynCo su ectopic beats?
  20. de novo
    from the beginning
    Spontaneous germ line mutations (sporadic de novo)nnFamilial mutationsnConfer – udelit…these mutations confer a leaky phenotype on the channelnAberrantnnVELMI DOLEZITE – relationship between leak and arrhythmia – how?
  21. elusiveness
    the quality of being difficult to grasp or pin down
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezac...
  22. heritable
    capable of being inherited
    Compendium – suhrn, zoznam, prehladnHeritable – vyslovnost?
  23. sequester
    keep away from others
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  24. incidence
    the relative frequency of occurrence of something
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  25. syncope
    the loss of sounds from within a word
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  26. aberrant
    markedly different from an accepted norm
    Spontaneous germ line mutations (sporadic de novo)nnFamilial mutationsnConfer – udelit…these mutations confer a leaky phenotype on the channelnAberrantnnVELMI DOLEZITE – relationship between leak and arrhythmia – how?
  27. susceptibility
    the state of being easily affected
    Confounding effectsnSusceptibilitynnArrhythmias in mice and patience with genetic mutations in RyR2 are almost always triggered by stress or catecholamines.
  28. familial
    relating to a social unit living together
    Spontaneous germ line mutations (sporadic de novo)nnFamilial mutationsnConfer – udelit…these mutations confer a leaky phenotype on the channelnAberrantnnVELMI DOLEZITE – relationship between leak and arrhythmia – how?
  29. putative
    purported
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezacgytitel...
  30. weaning
    the act of substituting other food for the mother's milk in the diet of a child or young mammal
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  31. precipitating
    bringing on suddenly or abruptly
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezac...
  32. confer
    present
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  33. elucidate
    make clear and comprehensible
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  34. elusive
    skillful at evading capture
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezac...
  35. pursuant
    in conformance to or agreement with
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezacgytitel...
  36. elicit
    call forth, as an emotion, feeling, or response
    To elicit..e.g iso elicited equal effects on heart ratesnTachycardia was induciblennThese findings siggest that this mutation in RyR2 enhances the susceptibility to arrhythmias in young mice and that the increased arrhythmogenic substrate in these mice might lead to the enhanced incidence of SIDS.
  37. auditory
    of or relating to the process of hearing
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezac...
  38. compendium
    a publication containing a variety of works
    Compendium – suhrn, zoznam, prehladnHeritable – vyslovnost?
  39. confounding
    that confounds or contradicts or confuses
    Confounding effectsnSusceptibilitynnArrhythmias in mice and patience with genetic mutations in RyR2 are almost always triggered by stress or catecholamines.
  40. sporadic
    recurring in scattered or unpredictable instances
    Spontaneous germ line mutations (sporadic de novo)nnFamilial mutationsnConfer – udelit…these mutations confer a leaky phenotype on the channelnAberrantnnVELMI DOLEZITE – relationship between leak and arrhythmia – how?
  41. inborn
    normally existing at birth
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezac...
  42. sequestered
    kept separate and secluded
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  43. sentinel
    a person employed to keep watch for some anticipated event
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezac...
  44. perturbation
    the act of causing disorder
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezacgytitel...
  45. elicited
    called forth from a latent or potential state by stimulation
    To elicit..e.g iso elicited equal effects on heart ratesnTachycardia was induciblennThese findings siggest that this mutation in RyR2 enhances the susceptibility to arrhythmias in young mice and that the increased arrhythmogenic substrate in these mice might lead to the enhanced incidence of SIDS.
  46. wean
    gradually deprive of mother's milk
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  47. genetic
    relating to the study of heredity and variation in organisms
    Confounding effectsnSusceptibilitynnArrhythmias in mice and patience with genetic mutations in RyR2 are almost always triggered by stress or catecholamines.
  48. ostensibly
    from appearances alone
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezac...
  49. enhanced
    increased or intensified in value or beauty or quality
    To elicit..e.g iso elicited equal effects on heart ratesnTachycardia was induciblennThese findings siggest that this mutation in RyR2 enhances the susceptibility to arrhythmias in young mice and that the increased arrhythmogenic substrate in these mice might lead to the enhanced incidence of SIDS.
  50. precipitate
    bring about abruptly
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezac...
  51. conform to
    behave in accordance or in agreement with
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  52. precede
    be earlier in time
    PrecedednPreponderantlynProspectivelynElectivelynProarrhythmogenicnSubsequentlynCo su ectopic beats?
  53. conform
    be similar, be in line with
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  54. beats
    a United States youth subculture of the 1950s
    PrecedednPreponderantlynProspectivelynElectivelynProarrhythmogenicnSubsequentlynCo su ectopic beats?
  55. germ
    a structure from which tissue can develop into an organism
    Spontaneous germ line mutations (sporadic de novo)nnFamilial mutationsnConfer – udelit…these mutations confer a leaky phenotype on the channelnAberrantnnVELMI DOLEZITE – relationship between leak and arrhythmia – how?
  56. prudent
    marked by sound judgment
    Prudent – preziravy, rozvaznynnnnn
  57. decisive
    characterized by resoluteness and firmness
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezac...
  58. sympathetic
    expressing compassion or friendly fellow feelings
    Exportnut zotero databazu na Amitov notebook!nnhypoxiannparasympathetic versus sympathetic tone?
  59. subsequently
    happening at a time later than another time
    PrecedednPreponderantlynProspectivelynElectivelynProarrhythmogenicnSubsequentlynCo su ectopic beats?
  60. reveal
    make visible
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  61. confound
    be confusing or perplexing to
    Confounding effectsnSusceptibilitynnArrhythmias in mice and patience with genetic mutations in RyR2 are almost always triggered by stress or catecholamines.
  62. reverse
    change to the contrary
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  63. induce
    cause to act in a specified manner
    Increased incidence of SIDS in mutant mice might be caused by cardiac arrhythmias that are induced under conditions of catecholaminergic stress.
  64. exertion
    use of physical or mental energy; hard work
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezac...
  65. render
    give or supply
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezacgytitel...
  66. induced
    brought about or caused; not spontaneous
    Increased incidence of SIDS in mutant mice might be caused by cardiac arrhythmias that are induced under conditions of catecholaminergic stress.
  67. reaction
    an idea evoked by some experience
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  68. relationship
    a mutual connection between people
    Spontaneous germ line mutations (sporadic de novo)nnFamilial mutationsnConfer – udelit…these mutations confer a leaky phenotype on the channelnAberrantnnVELMI DOLEZITE – relationship between leak and arrhythmia – how?
  69. rates
    a local tax on property (usually used in the plural)
    To elicit..e.g iso elicited equal effects on heart ratesnTachycardia was induciblennThese findings siggest that this mutation in RyR2 enhances the susceptibility to arrhythmias in young mice and that the increased arrhythmogenic substrate in these mice might lead to the enhanced incidence of SIDS.
  70. link
    connect, fasten, or put together two or more pieces
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  71. manifest
    clearly revealed to the mind or the senses or judgment
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezac...
  72. patience
    good-natured tolerance of delay or incompetence
    Confounding effectsnSusceptibilitynnArrhythmias in mice and patience with genetic mutations in RyR2 are almost always triggered by stress or catecholamines.
  73. event
    something that happens at a given place and time
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezac...
  74. fig
    Mediterranean tree widely cultivated for its edible fruit
    Opytat sa Anetty na ten fig.1 – nech mi to vysvetlinnWhere is cal2-binding domain?
  75. error
    a wrong action attributable to bad judgment or ignorance
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezac...
  76. performance
    the act of doing something successfully
    Ak ostane cas – co presne je PCR?, denaturing high performance liquid chromatographynnPreco 2. mutacia ma take iste mnozstvo cal2? (aktivita je vyssia aj bez PKA)nMissense mutationnMedicolegalnZistit ake su statistiky teraz (SIDS – 1/1000?)
  77. pace
    the relative speed of progress or change
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  78. model
    a representation of something, often on a smaller scale
    Gaburjakovej clanok o lum Ca – ako sa vola model flow through?
  79. effect
    a phenomenon that is caused by some previous phenomenon
    Confounding effectsnSusceptibilitynnArrhythmias in mice and patience with genetic mutations in RyR2 are almost always triggered by stress or catecholamines.
  80. chain
    a series of (usually metal) rings or links fitted into one another to make a flexible ligament
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  81. cause
    events that provide the generative force of something
    Increased incidence of SIDS in mutant mice might be caused by cardiac arrhythmias that are induced under conditions of catecholaminergic stress.
  82. risk
    a source of danger
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  83. remains
    the dead body of a human being
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezac...
  84. flow
    move along, of liquids
    Gaburjakovej clanok o lum Ca – ako sa vola model flow through?
  85. finding
    something that is discovered
    To elicit..e.g iso elicited equal effects on heart ratesnTachycardia was induciblennThese findings siggest that this mutation in RyR2 enhances the susceptibility to arrhythmias in young mice and that the increased arrhythmogenic substrate in these mice might lead to the enhanced incidence of SIDS.
  86. surface
    the outer boundary of an artifact or a material layer
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  87. conditions
    the context that influences the performance of a process
    Increased incidence of SIDS in mutant mice might be caused by cardiac arrhythmias that are induced under conditions of catecholaminergic stress.
  88. equal
    having the same quantity, value, or measure as another
    To elicit..e.g iso elicited equal effects on heart ratesnTachycardia was induciblennThese findings siggest that this mutation in RyR2 enhances the susceptibility to arrhythmias in young mice and that the increased arrhythmogenic substrate in these mice might lead to the enhanced incidence of SIDS.
  89. evidence
    knowledge on which to base belief
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezac...
  90. presence
    current existence
    SLOVICKA:nXander, 2009nnProspectively – nCo presne znamena heterozygousnIncidencenLittermatesnRevealnVentricular ectopynSurface ecgnIntracardiac pacingnReverse transcription-polymerase chain reactionnConfer – mutation confers an increased risk of cardiac arrhythmianElucidatenSequesterednTachycardianSyncopenEctopicnRevealed the presence ofnCausal linknConform tonWeaningnNeonatal versus postnatal???
  91. establish
    set up or found
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezac...
  92. bind
    secure with or as if with ropes
    Opytat sa Anetty na ten fig.1 – nech mi to vysvetlinnWhere is cal2-binding domain?
  93. tone
    the distinctive property of a complex sound
    Exportnut zotero databazu na Amitov notebook!nnhypoxiannparasympathetic versus sympathetic tone?
  94. beat
    hit repeatedly
    PrecedednPreponderantlynProspectivelynElectivelynProarrhythmogenicnSubsequentlynCo su ectopic beats?
  95. rate
    a quantity considered as a proportion of another quantity
    To elicit..e.g iso elicited equal effects on heart ratesnTachycardia was induciblennThese findings siggest that this mutation in RyR2 enhances the susceptibility to arrhythmias in young mice and that the increased arrhythmogenic substrate in these mice might lead to the enhanced incidence of SIDS.
  96. condition
    a mode of being or form of existence of a person or thing
    Increased incidence of SIDS in mutant mice might be caused by cardiac arrhythmias that are induced under conditions of catecholaminergic stress.
  97. might
    physical strength
    Increased incidence of SIDS in mutant mice might be caused by cardiac arrhythmias that are induced under conditions of catecholaminergic stress.
  98. position
    the particular part of space occupied by something
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezac...
  99. lead
    take somebody somewhere
    To elicit..e.g iso elicited equal effects on heart ratesnTachycardia was induciblennThese findings siggest that this mutation in RyR2 enhances the susceptibility to arrhythmias in young mice and that the increased arrhythmogenic substrate in these mice might lead to the enhanced incidence of SIDS.
  100. ten
    the cardinal number that is the sum of nine and one
    Opytat sa Anetty na ten fig.1 – nech mi to vysvetlinnWhere is cal2-binding domain?
  101. death
    the permanent end of all life functions in an organism
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezacgytitel...
  102. remain
    continue in a place, position, or situation
    Prone positionnInborn errors of metabolismnDecisive – rozhodujuci, presvedcivynElusive – tazko zachytitelne priciny, tazko postihnutelnennZase conferring – evidence establishing LQTS-conferring cardiac channel mutations as the ….or mechanism remains elusive (ja)nnPrecipitating event – vyvolavajuca udalostnnAuditory stimuli – sluchovy podnetnManifestnExertion – namahanSentinel event, sentinel = hliadka, straz, strazcanOstensibly – zdanlivo, udajnenElusiveness – nepostihnutelnost, nezac...
  103. line
    a length between two points
    Spontaneous germ line mutations (sporadic de novo)nnFamilial mutationsnConfer – udelit…these mutations confer a leaky phenotype on the channelnAberrantnnVELMI DOLEZITE – relationship between leak and arrhythmia – how?
  104. almost
    slightly short of or not quite accomplished; all but
    Confounding effectsnSusceptibilitynnArrhythmias in mice and patience with genetic mutations in RyR2 are almost always triggered by stress or catecholamines.
Created on Sat Feb 13 21:12:19 EST 2010 (updated Sat Feb 13 21:22:57 EST 2010)

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