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- apogee the farthest point in an orbit around the Earth
- Epigaea small creeping evergreen shrubs: trailing arbutus
- apache a Parisian gangster
- Apache any member of Athapaskan tribes that migrated to the southwestern desert (from Arizona to Texas and south into Mexico); fought a losing battle from 1861 to 1886 with the United States and were resettled in Oklahoma
- opaque not transmitting or reflecting light or radiant energy
- abaca Philippine banana tree having leafstalks that yield Manila hemp used for rope and paper etc
- appanage a grant (by a sovereign or a legislative body) of resources to maintain a dependent member of a ruling family
- apanage a grant (by a sovereign or a legislative body) of resources to maintain a dependent member of a ruling family
- apogamy development of an embryo without fertilization
- apogean relating to or characteristic of an apogee
- obeche large west African tree having large palmately lobed leaves and axillary cymose panicles of small white flowers and one-winged seeds; yields soft white to pale yellow wood
- aback by surprise
- epoch a period marked by distinctive character
- APC a drug combination found in some over-the-counter headache remedies (aspirin and phenacetin and caffeine)
- apologue a short moral story (often with animal characters)
- apocope abbreviation of a word by omitting the final sound or sounds
- obechi large west African tree having large palmately lobed leaves and axillary cymose panicles of small white flowers and one-winged seeds; yields soft white to pale yellow wood
- Apogon type genus of the Apogonidae
- epic a long narrative poem telling of a hero's deeds
- OPCW international organization for chemical disarmament
