- Types:
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endonuclease
a nuclease that cleaves nucleic acids at interior bonds and so produces fragments of various sizes
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exonuclease
a nuclease that releases one nucleotide at a time (serially) beginning at one of a nucleic acid
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restriction endonuclease, restriction enzyme, restriction nuclease
any of the enzymes that cut nucleic acid at specific restriction sites and produce restriction fragments; obtained from bacteria (where they cripple viral invaders); used in recombinant DNA technology