A manuscript is a handwritten work. It's still a manuscript if it's typed — if a publisher asks for your manuscript, don't send her something scrawled on notebook paper!
The noun manuscript evolved from the Latin manu scriptus, meaning “written by hand.” Manu is “hand” and scriptus is “to write." It refers to old documents actually written by hand before books were made, but it can also refer to a writer's unpublished work whether it's handwritten or typed. Samuel Johnson said, “Your manuscript is both good and original, but the part that is good is not original and the part that is original is not good.” Harrumph!
