Loathsome things are things people hate — so much they make you want to throw up.
Something loathsome is disgusting, distasteful, foul, revolting, and yucky. It's probably gross and awful, too. Some loathsome things are even repellent and nauseating. Other times, this word has a more general meaning. A corrupt politician is considered loathsome because he has no morals. A murderer is loathsome because of his crimes. Anything you think is horrible could be called loathsome.
